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The research of Prof. Witkamp is aimed at generating knowledge necessary for the development of technologies allowing atom- and energy efficient recovery of materials in pure form (water, salts, metals) from a wide variety of sources, and to realise such technologies in practice at appropriate scales through translational research. Concepts include the Water Refinery, Eutectic Freeze Crystallization, (ultra)trace compound detection and recovery, Natural Deep Eutectic Solvents (NADES's) and supercritical carbon dioxide based processes.