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Professor Saikaly's research focuses on integrating cutting-edge -omic tools (genomic, proteomic, and transcriptomic) with bioprocess engineering to optimize and create sustainable biotechnologies for wastewater reclamation and reuse that are robust, scalable, and capable of providing tailored water quality with minimization of energy, resources, and carbon footprint. He is guided by the vision that gaining a better insight of the microbial ecology of microorganisms and the variables that affect their ecophysiology will allow us to fully harness their potential in environmental biotechnology.