Inspired by the model of evolutionary biological systems, the Khashab research group is engaged in the design and synthesis of supramolecular assemblies at the nanoscale employing non-covalent and coordination interactions. The main advantage of these molecularly defined entities is superior solution processability to be easily and reproducibly integrated in future commercial fabrication processes. These systems are designed with an emphasis on hierarchical-assembly (evolution), porosity (ordered self-assembly) and stimuli-responsiveness (smart materials).